ovu.com - OVU.com

Gestational Glucose: Sugar’s Impact on Pregnancy

Gestational Glucose: Sugar’s Impact on Pregnancy

The sweet allure of sugar is hard to resist, especially during pregnancy when cravings kick in. But as gestational glucose levels rise, so do concerns about the well–being of both mother and fetus. In this comprehensive guide, we’ll delve into the effects of sugar on pregnancy, offering insights and strategies to ensure the health of both expectant mothers and their babies.

Understanding Gestational Glucose

Gestational glucose refers to the sugar utilized by both the mother and the developing fetus. While glucose is a vital source of energy, pregnancy demands a delicate balance. The body naturally becomes more insulin resistant during pregnancy to provide the fetus with an adequate glucose supply, which can present challenges if maternal sugar intake is high.

Sugar and Fetal Development

The impact of sugar extends beyond the mother. High maternal blood sugar levels are associated with risks such as excessive birth weight and other adverse outcomes, an increased risk of developing asthma in and other common allergies, including allergic rhinitis, atopy and eczema, wheeze, and food allergies in the child [8]. Furthermore, sugar consumption during pregnancy may contribute to increased gestational weight gain and the development of pregnancy complications, including gestational diabetes, preeclampsia and preterm birth. Moderation is crucial to safeguard the growing life inside.

The Hidden Risks of Sugar: Gestational Diabetes and Beyond

Gestational diabetes, also known as gestational diabetes mellitus (GDM) is diabetes that develops during pregnancy in women who have not been previously diagnosed with type 1 or type 2 diabetes [4]. Affecting an estimated 6–18% of all pregnancies based on traditional diagnostic criteria (although it may be higher if more inclusive criteria are used), GDM poses significant risks to both mother and child. Pregnant women with gestational diabetes are at increased risk for maternal and fetal complications, including preeclampsia, fetal macrosomia (which can cause shoulder dystocia and birth injury), neonatal hypoglycemia, and even preterm birth [4]. 

Moreover, when metabolic complications from GDM are identified and managed later in pregnancy, the risk of adverse outcomes increases, with rates of toxemia at 29.7%, premature labor at 21.8%, cesarean section at 23.8%, perinatal mortality at 2.9%, congenital anomalies at 5.9%, and the likelihood of babies being large for their gestational age at 32.7% [9].

Beyond the immediate dangers perinatal, such as preeclampsia and birth injuries due to fetal macrosomia, GDM is linked to a heightened probability of metabolic diseases later in life for both parties. Addressing this, experts highlight the importance of managing blood glucose levels diligently to mitigate these risks.

Navigating the Glucose Tide: Screening and Diagnosis of GDM

With the prevalence of GDM on the rise, timely screening and diagnosis are critical. The U.S. Preventive Services Task Force (USPSTF) recommends screening for gestational diabetes in asymptomatic pregnant women at 24 weeks of gestation or later to optimize maternal and fetal outcomes [4]. Yet, the protocols for screening/diagnosing GDM are controversial and still remain a matter of debate, underlining the necessity for standardized global practices.

In Pursuit of Balance: Treating Gestational Diabetes

Initial GDM treatment strategies revolve around diet and exercise. Should these initial measures fall short in controlling glucose levels, medical intervention may be necessary [5]. The utilization of medications such as metformin or insulin analogs is then considered, which have been deemed both safe and effective during pregnancy. Notably, insulin analogs, being closer to endogenous insulin than regular human insulin, carry a lower risk of hypoglycemia and may provide improved glycemic control. Insulin lispro, aspart, and detemir have received approval for pregnancy use, and while insulin glargine isn’t officially approved, available research hasn’t indicated major contraindications. Moreover, the oral hypoglycemic agents glyburide and metformin are also considered safe and efficacious for managing GDM [6].

For those at the prediabetes stage, an aggressive approach with lifestyle modifications coupled with metformin can help to prevent or delay progression to type 2 diabetes [5]. Noteworthy is the advantage of insulin analogs; they not only enhance glycemic control but also reduce the risk of hypoglycemic episodes, thereby presenting a safer profile for both mother and fetus. 

The Tech–Enabled Future: Continuous Glucose Monitoring in Pregnancy

In the fight against the hyperglycemic intrauterine environment often seen in pregnancies complicated by gestational diabetes mellitus (GDM) — which may contribute to the wider epidemic of type 2 diabetes mellitus (T2DM) — continuous glucose monitoring (CGM) stands out as a groundbreaking tool, particularly for managing diabetes in pregnancy, including those with abnormal glucose tolerance or diagnosed type 1 diabetes [7]. CGM, now specifically approved for pregnant women, surpasses traditional self–monitoring of blood glucose (SMBG) by providing real–time, detailed insights into glucose fluctuations with a much higher data density — up to 288 readings per day compared to the 7 typically collected by SMBG [10]. This information not only offers a deeper understanding of glucose metabolism in pregnancy but also empowers healthcare providers to make more informed decisions regarding pharmacologic interventions. Such interventions, informed by CGM’s capability to detect often overlooked postprandial and nocturnal hyperglycemia, have been associated with a lower risk of neonatal complications, such as babies born large for gestational age [1], [2]. The continuous data stream from CGM acts as both a “roadmap for effective self–management” and a crucial step towards optimizing diabetes treatment in pregnancy, aiming to safeguard maternal and fetal health by maintaining glucose levels within the target range and minimizing the risk of complications [10]. 

Managing Sweet Cravings

Cravings for sugary treats can be intense during pregnancy, as hormonal changes may intensify the desire for sweets. Rather than succumbing to processed sweets, which offer little nutritional benefit and can lead to spikes in blood sugar, opt for natural alternatives like fresh and dried fruit, which provide essential vitamins, minerals and fiber. Yogurt can be an excellent choice too, especially if it contains probiotics, which support digestive health. Small portions of dark chocolate not only satisfy the craving but also supply antioxidants. Moreover, integrating whole grains and lean proteins into your diet can help stabilize blood sugar levels and reduce the frequency and intensity of sweet cravings. It's also helpful to stay hydrated, as sometimes thirst can be mistaken for hunger or cravings. By finding the right balance and making smart choices, you can manage your cravings while nourishing both your body and your growing baby.

Reading Labels and Understanding Sugar Content

Sugar hides in many processed foods, often under names like sucrose, fructose, or corn syrup. Learning to read and understand food labels is essential for managing sugar intake, allowing for informed decisions about what to eat.

The Role of Artificial Sweeteners

The safety of artificial sweeteners during pregnancy remains a topic of active discussion among healthcare professionals. Some artificial sweeteners have been deemed safe in moderation by regulatory agencies such as the FDA, yet natural alternatives like stevia are often recommended because they originate from plant sources and are perceived to have a better safety profile. Nonetheless, the research on all sweeteners is continually evolving, and what is considered safe today may be reevaluated with new data tomorrow. The most reliable course of action for expectant mothers is to consult with their healthcare provider before incorporating any sweeteners into their diet. This ensures that their choices are informed by the latest research and tailored to their individual health needs, offering the safest options for themselves and their developing baby. 

Guidance from Medical Experts 

Leading health organizations, including the American College of Obstetricians and Gynecologists, recommend that pregnant women be mindful of their sugar intake and focus on consuming high–quality calories. Regular consultations with healthcare providers and thorough prenatal care are essential for managing sugar intake effectively during pregnancy. These experts also emphasize the importance of a balanced diet rich in whole foods, which can provide essential vitamins and minerals while helping to curb excessive sugar cravings, ensuring optimal outcomes for both mother and child.

Daily Sugar Intake During Pregnancy

Nutritional guidelines for sugar intake during pregnancy align with the overarching principle of moderation. The World Health Organization (WHO) advises that for optimal health outcomes, sugar should constitute less than 10% of one’s total daily caloric intake, noting additional benefits when this is reduced to below 5%. This is approximately equivalent to 25 grams, or 6 teaspoons, of sugar per day. Pregnant women, however, need to be particularly vigilant due to the insulin resistance caused by hormonal shifts, which can lead to elevated blood sugar levels. As a precaution, maintaining fasting blood glucose below 95mg/dL, and post–meal levels beneath 140mg/dL and 120mg/dL after one and two hours, respectively, is recommended during pregnancy. This careful monitoring is vital given the heightened risks linked to excessive sugar consumption during this time. A balanced diet rich in fruits, vegetables, whole grains, and lean proteins can help meet nutritional demands and curb sugar cravings. Given that each pregnancy is unique, consulting with a registered dietitian or healthcare provider is vital to ensure dietary choices are appropriately tailored to support both mother’s–to–be and growing fetus health.

 

Wrapping Things Up 

Although it might be so tempting to eat one raspberry cupcake in the morning and add one slice of cake during brunch, when you are expecting, it is essential to remember that you are not alone in your body, thus, responsible not only for your health but also for the health of your unborn baby. That is why, before taking something sweet in your hands and push closer a cup of steaming tea for making the most of this moment, hold on for just a minute and explore the sugar content you are going to eat. 

It doesn’t mean that you should avoid sweet cravings completely. For Birthdays, Baby Showers, festive season holidays, office celebrations and other big events it’s perfectly reasonable to partake in a modest treat. The key lies in moderation and the quality of the indulgence. Opting for sweets made with natural sugars, enjoying smaller portions, or choosing treats enriched with nutrients can satisfy your cravings without compromising health standards. It’s all about striking a balance that honors both your needs and those of your baby, ensuring that celebrations can still be savored with joy and health in harmony. Always confer with your healthcare provider to personalize your dietary approach, ensuring that your moments of indulgence are both enjoyable and prudent.

 

References: 

1. O’Malley, G., Wang, A., Ogyaadu, S., & Levy, C. J. (2021). Assessing Glycemic Control Using CGM for Women with Diabetes in Pregnancy. Current Diabetes Reports, 21(11), 44. https://doi.org/10.1089/dia.2020.0667 

PubMed: https://pubmed.ncbi.nlm.nih.gov/34735626/ 

2. Yamamoto, J. M., & Murphy, H. R. (2021). Benefits of Real-Time Continuous Glucose Monitoring in Pregnancy. Diabetes Technology & Therapeutics, 23(S1), S8-S14. https://doi.org/10.1089/dia.2020.0667 

PubMed: https://pubmed.ncbi.nlm.nih.gov/33512267/ 

3. Trumpff, C., Sturm, G., Picard, M., Foss, S., Lee, S., Feng, T., Cardenas, A., McCormack, C., Champagne, F. A., & Monk, C. (2021). Added sugar intake during pregnancy: Fetal behavior, birth outcomes, and placental DNA methylation. Developmental Psychobiology, 63(5), 878-889. https://doi.org/10.1002/dev.22088 

PubMed: https://pubmed.ncbi.nlm.nih.gov/33415750/ 

4. US Preventive Services Task Force, Davidson, K. W., Barry, M. J., Mangione, C. M., Cabana, M., Caughey, A. B., ... & Wong, J. B. (2021). Screening for Gestational Diabetes: US Preventive Services Task Force Recommendation Statement. JAMA, 326(6), 531-538. https://doi.org/10.1001/jama.2021.11922 

PubMed: https://pubmed.ncbi.nlm.nih.gov/34374716/ 

5. Mack, L. R., & Tomich, P. G. (2017). Gestational Diabetes: Diagnosis, Classification, and Clinical Care. Obstetrics and Gynecology Clinics of North America, 44(2), 207-217. https://doi.org/10.1016/j.ogc.2017.02.002 

PubMed: https://pubmed.ncbi.nlm.nih.gov/28499531/ 

6. Alfadhli, E. M. (2015). Gestational diabetes mellitus. Saudi Medical Journal, 36(4), 399-406. https://doi.org/10.15537/smj.2015.4.10307 

PubMed: https://pubmed.ncbi.nlm.nih.gov/25828275/ 

7. Zhu, Y., & Zhang, C. (2016). Prevalence of Gestational Diabetes and Risk of Progression to Type 2 Diabetes: a Global Perspective. Current Diabetes Reports, 16(1), 7. https://doi.org/10.1007/s11892-015-0699-x 

PubMed: https://pubmed.ncbi.nlm.nih.gov/26742932/ 

8. Gupta, A., Singh, A., Fernando, R. L., Dharmage, S. C., Lodge, C. J., & Waidyatillake, N. T. (2022). The association between sugar intake during pregnancy and allergies in offspring: a systematic review and meta-analysis of cohort studies. Nutrition Reviews, 80(4), 904-918. https://doi.org/10.1093/nutrit/nuab052 

PubMed: https://pubmed.ncbi.nlm.nih.gov/34432049/ 

9. Semmler, K., Semmler, S., Steindel, E., Lambeck, M., & Minkwitz, H. G. (1990). [Early detection of diabetes in pregnancy—a factor for reducing perinatal mortality and morbidity]. Zentralblatt für Gynäkologie, 112(11), 697-705.

PubMed: https://pubmed.ncbi.nlm.nih.gov/2205072/ 

10. Hewapathirana, N. M., O'Sullivan, E., & Murphy, H. R. (2013). Role of continuous glucose monitoring in the management of diabetic pregnancy. Current Diabetes Reports, 13(1), 34-42. https://doi.org/10.1007/s11892-012-0337-9 

PubMed: https://pubmed.ncbi.nlm.nih.gov/23081851/

Get a Free Quote


Enter your phone in an international format
Please fill your county of residence so we can match you with best clinic
The more detailed address you put for a preferred destination for your treatment - the more options you will get