IVF Cost in Bulgaria: ReproBioMed Clinic

Meet ReproBioMed Medical Center (Sofia, Bulgaria) & its 10 IVF Bundles. 

• 3 Natural IVF Bundles. 
• 2 Classic IVF packs. 
• 2 IVF–ICSI Bundles. 
• 1 PICSI pack that adjusts any IVF program you select. 

IVF Bundles that Work Wonders. With Ease and Seamless Dragging, Dropping, Rotating, Attaching, or Detaching Options, all Bundles introduce powerful features to get your IVF done successfully. Discover all features and explore which pack is right for you. Learn all about your spending. Starting at 750.00 EUR for Natural IVF cycle; 1,000.00 EUR for Classic IVF, and 1,150.00 EUR for IVF–ICSI.

Introducing ReproBioMed Medical Center located in Sofia, Bulgaria.

ReproBioMed Medical Center (Sofia, Bulgaria) specializes in performing: 

• Consultations and Screenings; 
• Infertility Screening and Treatment (Gynecology, Andrology, Urology); 
• Lab. Tests; 
• Surgeries; 
• Ovulation Induction (OI) cycles; 
• IUI (Intrauterine Insemination) cycles: non–stimulated, stimulated, with the partner’s or using the donor’s sperm; 
• IVF/ICSI/PICSI cycles (natural (non–stimulated), stimulated, with the partner’s or using the donor’s sperm;
• Preimplantation Genetic Testing; 
• Surgical Sperm Retrieval (TESE, MESA); 
• Egg Donation cycles (on demand); 
• Sperm Donation cycles; 
• FET cycles; 
• Oocyte & Embryo Vitrification/Sperm Freezing & Storage cycles; 
• Prenatal Screenings; 
• Labor & Delivery; 
• Postnatal Screenings.

IVF programs and their costs.

Natural IVF cycle using own oocytes and the partner’s sperm.

• Pack #1: Natural IVF–ICSI cycle using own oocytes and the partner’s sperm with 1 fresh ET: 1 ovulation cycle tracking session (Follicle Tracking ultrasound scans, blood tests), 1 Oocyte Retrieval session, 1 ICSI–Embryo Generation session, 1 embryonic cohort cultivation session, and 1 fresh ET using 1 or 2 fresh embryos (EmbryoGlue is not included) Bundle’s cost starts at 750.00 EUR (1,500.00 BGN) per cycle. 
• Pack #2: Natural IVF–ICSI cycle using own oocytes and the partner’s sperm with 1 fresh ET: 1 ovulation cycle tracking session (Follicle Tracking ultrasound scans, blood tests), 1 Oocyte Retrieval session, 1 ICSI–Embryo Generation session, 1 embryonic cohort cultivation session, and 1 fresh ET using 1 or 2 fresh embryos (EmbryoGlue is included) Bundle’s cost starts at 775.00 EUR (1,550.00 BGN) per cycle. 
• Pack #3: Natural IVF–ICSI using own oocytes and the partner’s sperm without ET: 1 COS cycle with its clinical management and monitoring, 1 Oocyte Retrieval session, 1 ICSI–Embryo Generation session, and 1 embryonic cohort cultivation session. Bundle’s cost starts at 650.00 EUR (1,300.00 BGN) per cycle. 

Classic IVF using own oocytes and the partner’s sperm.

• Pack #1: IVF using own oocytes and the partner’s sperm with 1 fresh ET: 1 COS cycle (clinical management & monitoring), 1 Oocyte Retrieval session (included), 1 conventional IVF–Embryo Generation session, 1 embryonic cohort cultivation session, and 1 fresh ET using 1 or 2 fresh embryos (EmbryoGlue is not included) Bundle’s cost starts at 1,000.00 EUR (2,000.00 BGN) per cycle. 
• Pack #2: IVF using own oocytes and the partner’s sperm with 1 fresh ET: 1 COS cycle (clinical management & monitoring), 1 Oocyte Retrieval session (included), 1 conventional IVF–Embryo Generation session, 1 embryonic cohort cultivation session, and 1 fresh ET using 1 or 2 fresh embryos (EmbryoGlue is included) Bundle’s cost starts at 1,025.00 EUR (2,050.00 BGN) per cycle. 

IVF–ICSI using own oocytes and the partner’s sperm.

• Pack #1: IVF–ICSI using own oocytes and the partner’s sperm with 1 fresh ET: 1 COS cycle with its clinical management and monitoring, 1 Oocyte Retrieval session, 1 ICSI–Embryo Generation session, 1 embryonic cohort cultivation session, and 1 fresh ET using 1 or 2 fresh embryos (EmbryoGlue is not included) Bundle’s cost starts at 1.150.00 EUR (2,300.00 BGN) per cycle. 
• Pack #2: IVF–ICSI using own oocytes and the partner’s sperm with 1 fresh ET: 1 COS cycle with its clinical management and monitoring, 1 Oocyte Retrieval session, 1 ICSI–Embryo Generation session, 1 embryonic cohort cultivation session, and 1 fresh ET using 1 or 2 fresh embryos (EmbryoGlue is included) Bundle’s cost starts at 1.175.00 EUR (2,350.00 BGN) per cycle.

What is not in the Bundle? 

IVF extras and their fees: 

• Transvaginal ultrasound–guided follicular puncture (local anesthetic is included) without Oocyte Cultivation — 225.00 EUR (450.00 EUR).
• Transvaginal ultrasound–guided follicular puncture (local anesthetic is included) with oocyte cultivation — 325.00 EUR (650.00 EUR).
• Classic IVF: 1 conventional IVF–Embryo Generation session and Embryo Cultivation Bundle’s cost starts at 550.00 EUR (1,100.00 BGN) per cycle. 
• IVF–ICSI: 1 ICSI–Embryo Generation session, and Embryo Cultivation Bundle’s cost starts at 850.00 EUR (1,700.00 BGN) per cycle. 
• Physiological Intracytoplasmic Sperm Injection (PICSI) — 50.00 EUR (100.00 BGN).
• Embryo Transfer (without EmbryoGlue) — 200.00 EUR (400.00 BGN).
• Embryo Transfer (with EmbryoGlue) — 225.00 EUR (450.00 BGN). 
• EmbryoGlue — 25.00 EUR (50.00 BGN). 
• Mock Embryo Transfer (Mock–ET) — 75.00 EUR (150.00 BGN). 
• Extra Embryo Transfer Catheter — 15.00 EUR (30.00 BGN). 
• Laser–Assisted Hatching (LAH) — 125.00 EUR (250.00 BGN).
• Polar Body Biopsy (The polar body technique makes use of the 23 chromosomes contained in the first polar body)/ Blastomere 
• Biopsy/Trophectoderm Biopsy for Preimplantation Genetic Diagnosis/Screening — 250.00 EUR (500.00 BGN). 
• Intravenous anesthetics — 75.00 EUR (150.00 BGN). 

Ob.–Gyn. (Female Screening): 

• Express consultation with Ob.–Gyn. (10 min.) — 12.50 EUR (25.00 BGN). 
• Express consultation with Ob.–Gyn. (20 min.) — 20.00 EUR (40.00 BGN). 
• Ob.–Gyn. exam — 20.00 EUR (40.00 BGN). 
• Ob.–Gyn. + ultrasound scan — 37.50 EUR (75.00 BGN). 
• Antral Follicle Count (AFC) Test (Folliculometry; Follicle Ultrasound; Follicle Tracking ultrasound scan) — 20.00 EUR (40.00 BGN). 
• Colposcopy — 22.50 EUR (45.00 BGN).
• Cervical biopsy including Colposcopy and cervical tissue testing — 55.00 EUR (110.00 BGN). 
• Hysterosalpingogram (HSG; designed to detect blockages in the fallopian tubes) — 95.00 EUR (190.00 BGN). 

Ob.–Gyn. Surgeries:

• Diagnostic Laparoscopy — 450.00 EUR (900.00 BGN). 
• Operative Laparoscopy — 550.00 EUR (1,100.00 BGN). 
• Laparoscopic Hysterectomy — 750.00 EUR (1,500.00 BGN). 
• Tubal Plastic Surgery/Fallopian Tube Surgery and the other surgeries — 750.00 EUR (1,500.00 BGN). 

Consultations: 

• Consultation with Immunologist — 20.00 EUR (40.00 BGN). 
• Consultation with Geneticist — 20.00 EUR (40.00 BGN). 

Andrology (Male Screening & Treatment): 

• Consultation with Andrologist/Urologist + medical history review — 15.00 EUR (30.00 BGN). 
• Consultation with Andrologist/Urologist + male exam — 20.00 EUR (40.00 BGN). 
• Consultation with Andrologist/Urologist + ultrasound scan — 25.00 EUR (50.00 BGN). 
• Semen Analysis/Spermiogram (Volume of the sperm sample, Sperm cell motility, Sperm count) — 25.00 EUR (50.00 BGN). 
• Semen Analysis/Spermiogram (Volume of the sperm sample, Sperm cell motility, Sperm count, and Sperm morphology evaluation of sperm morphology using Kruger’s sperm function test) — 55.00 EUR (110.00 BGN). 
• Semen Analysis/Spermiogram (Volume of the sperm sample, Sperm cell motility, Sperm count, and Sperm morphology evaluation of sperm morphology using Kruger’s sperm function test + 24 hours sperm survival test) — 82.50 EUR (165.00 BGN). 
• 24 hours sperm survival test — 30.00 EUR (60.00 BGN). 
• Sperm DNA fragmentation test (The Sperm Chromatin Dispersion Test) — 60.00 EUR (120.00 BGN). 
• MACS sperm sorting (Magnetic Activated Cell Sorting separates sperm by density gradient and molecular filtration to remove apoptotic sperm, which is associated with DNA damage) GMP Annexin V Apoptosis Staining / Detection Kit — 110.00 EUR (220.00 BGN). 
• TESE (Testicular Sperm Extraction involves making a small incision in the testis and examining the tubules for the presence of sperm followed by Sperm Collection + Sperm Retrieval + fine–needle aspiration cytology with examination and histological diagnosis) — 400.00 EUR (800.00 BGN). 
• MESA (Microsurgical Epididymal Sperm Aspiration involves using a surgical microscope to open the small tubes within the epididymis to look for sperm and an incision in the scrotum to gain access to one or both testicles to collect sperm + fine–needle aspiration cytology with examination and histological diagnosis) — 400.00 EUR (800.00 BGN). 
• The Donor’s Sperm (1 vial) — 110.00 EUR (220.00 BGN). 

Laboratory: 

• Complete Blood Count (CBC) Test — 6.00 EUR (12.00 BGN). 
• Blood Biochemistry Test/Biochemical profile — 12.50 EUR (25.00 BGN). 
• Blood Biochemistry Test/Biochemical profile + Cholesterol Test + Triglycerides Test — 15.00 EUR (30.00 BGN). 
• Blood Type Test/Blood Typing + Rh factor — 12.50 EUR (25.00 BGN). 
• Clotting Time Test — 3.00 EUR (6.00 BGN). 
• Prothrombin Time (PT/INR) Blood Test for Clotting Time — 3.00 EUR (6.00 BGN). 
• Luteinizing Hormone (LH) Test — 10.00 EUR (20.00 BGN). 
• Estradiol blood test — 10.00 EUR (20.00 BGN). 
• Follicle–Stimulating Hormone (FSH) Levels Test — 10.00 EUR (20.00 BGN). 
• Prolactin Levels Test — 10.00 EUR (20.00 BGN). 
• Serum Progesterone Test — 10.00 EUR (20.00 BGN). 
• Testosterone Levels Test — 10.00 EUR (20.00 BGN). 
• Thyroid–Stimulating Hormone (TSH) Test — 10.00 EUR (20.00 BGN). 
• Triiodothyronine (T3) Test — 10.00 EUR (20.00 BGN). 
• Thyroxine (T4) Test — 10.00 EUR (20.00 BGN). 
• Thyroid Function Tests (TSH, FT4, FT3): Triiodothyronine (T3) Test — 10.00 EUR (20.00 BGN). 
• Thyroid Function Tests (TSH, FT4, FT3): Thyroxine (T4) Test — 10.00 EUR (20.00 BGN). 
• Quantitative hCG Blood Pregnancy Test: Beta HCG Test (β–hCG) — 10.00 EUR (20.00 BGN). 
• Anti–Müllerian Hormone Test (blood test designed to screen the ovarian reserve) — 15.00 EUR (30.00 BGN).
• Serum Inhibin B Levels Test (Inhibin–B as a test of ovarian reserve for women) — 27.50 EUR (55.00 BGN). 
• Anti–Müllerian Hormone Test + Inhibin–B Test — 27.50 EUR (55.00 BGN).

STD Screening panel (Sexually Transmitted Diseases): 

• Anti–HBc: Hepatitis B antibodies (Anti–HBcAg–total) — 15.00 EUR (30.00 BGN). 
• Hepatitis B surface antigen (HBsAg) test — 10.00 EUR (20.00 BGN). 
• Anti–HCV screening (Hepatitis C) — 10.00 EUR (20.00 BGN). 
• HIV I & II — 10.00 EUR (20.00 BGN). 
• Syphilis — 7.50 EUR (15.00 BGN). 

Urine tests: 

• Urine test — 3.50 EUR (7.00 BGN).
• Creatinine urine test/Urine Calcium Level Tests/Phosphorus Urine Test — 4.00 EUR/each test (8.00 BGN/each test). 

Immunology: 

• Recurrent Pregnancy Loss Panel Test (includes Immunological Tests: Antiphospholipid Antibody (APA), ТАТ, МАТ, Leukocyte Composition, and Immunophenotype of the Blood); Coagulation: Prothrombin Time (PT/INR) Blood Test for Clotting Time; Genetic Screenings; Vitamin D levels; and Homocysteine) — 235.00 EUR (470.00 BGN). 
• Embryo Implantation Failure Test/ Recurrent Implantation Failure Screening panel (includes Immunological Tests: Antiphospholipid Antibody (APA), ТАТ, МАТ, Leukocyte Composition, and Immunophenotype of the Blood); Coagulation: Prothrombin Time (PT/INR) Blood Test for Clotting Time; Vitamin D levels; and Homocysteine) — 135.00 EUR (270.00 BGN).

Microbiology: 

• Microbiology analysis + Antibiogram of cytology, urine or semen sample — 12.00 EUR (24.00 BGN). 
• Microbiology analysis + Antibiogram of cytology, urine or semen sample + Candidiasis Infection Screening + Trichomonas Infection Screening — 18.00 EUR (36.00 BGN). 
• Mycoplasma Infection Screening + Antibiogram — 15.00 EUR (30.00 BGN).
• Candidiasis Infection Screening + Trichomonas Infection Screening — 5.50 EUR (11.00 BGN). 
• Microbiology analysis + Antibiogram of cytology, urine or semen sample + Mycoplasma Infection Screening + Ureaplasma Infection Screening + Candidiasis Infection Screening + Trichomonas Infection Screening — 30.00 EUR (60.00 BGN). 

Genetic Screenings for infertility: 

• Non–Invasive Y–Chromosomal Microdeletions Profiling (male infertility screening) — 75.00 EUR (150.00 BGN). 
• Chromosome Analysis/Cytogenetic Analysis for Suspected Chromosomal Abnormalities (Karyotyping) — 85.00 EUR (170.00 BGN).

Preimplantation Genetic Testing (PGT):

• PGS using NGS (for 1 embryo) — 360.00 EUR (720.00 BGN). 
• PGS using NGS (for 2 embryos) — 720.00 EUR (1,440.00 BGN). 
• PGS using NGS (for 3 embryos) — 1,080.00 EUR (2,160.00 BGN). 
• PGS using NGS (for 4 embryos) — 1,440.00 EUR (2,880.00 BGN). 
• PGS using NGS (for 5 embryos) — 1,800.00 EUR (3,600.00 BGN). 
• PGS using NGS (for 6 embryos) — 2,160.00 EUR (4,320.00 BGN). 
• PGS using NGS (for 7 embryos) — 2,520.00 EUR (5,040.00 BGN). 
• PGS using NGS (for 8 embryos) — 2,880.00 EUR (5,760.00 BGN). 

PGT + Embryo Vitrification: 

• PGS–NGS + Vitrification (1 embryo) — 435.00 EUR (870.00 BGN).
• PGS–NGS + Vitrification (2 embryos) — 820.00 EUR (1,640.00 BGN). 
• PGS–NGS + Vitrification (2 embryos) — 1,205.00 EUR (2,410.00 BGN). 
• PGS–NGS + Vitrification (4 embryos) — 1,590.00 EUR (3,180.00 BGN). 
• PGS–NGS + Vitrification (5 embryos) — 1,975.00 EUR (3,950.00 BGN).
• PGS–NGS + Vitrification (6 embryos) — 2,360.00 EUR (4,720.00 BGN).
• PGS–NGS + Vitrification (7 embryos) — 2,745.00 EUR (5,490.00 BGN).
• PGS–NGS + Vitrification (8 embryos) — 3,130.00 EUR (6,260.00 BGN). 

Infectious Disease Genetic Testing: DNA tests: 

• Human papillomavirus genotype–specific risk (HPV) screening 16, 18, 31, 33, 35, 39, 45, 52, 56, 58, 59, 65 — 40.00 EUR (80.00 BGN).
• Chlamydia Antibody Panel, IgG & IgM (Evaluation of Chlamydia immunoglobulin M (IgM), IgG, and IgA using PCR) — 17.50 EUR (35.00 BGN). 

FET cycle. 

• Pack #1: FET cycle: 1 endometrial prep. for FET cycle, 1 Devitrification session powered up for fertilized oocytes/embryos, and 1 ET using 1 or 2 embryos (without EmbryoGlue) Bundle’s cost starts at 250.00 EUR (500.00 BGN) per cycle.
• Pack #2: FET cycle: 1 endometrial prep. for FET cycle, 1 Devitrification session powered up for fertilized oocytes/embryos, and 1 ET using 1 or 2 embryos (with EmbryoGlue) bundle’s cost starts at 275.00 EUR (550.00 BGN) per cycle.

Egg Freezing: 

• Egg Vitrification (up to 4 oocytes will be vitrified in cryogenic vial(s)/cryotube(s)/cryogenic tube(s)) + 6 months of storage in the cryobank — 250.00 EUR (500.00 BGN).
• Egg Vitrification (5–8 oocytes will be vitrified in cryogenic vial(s)/cryotube(s)/cryogenic tube(s)) + 6 months of storage in the cryobank — 300.00 EUR (600.00 BGN).
• Egg Vitrification (9 and more oocytes (large cohort) will be vitrified in cryogenic vial(s)/cryotube(s)/cryogenic tube(s)) + 6 months of storage in the cryobank — 350.00 EUR (700.00 BGN).

Sperm Freezing: 

• Sperm Freezing for ART — 75.00 EUR (150.00 BGN).
• Sperm Freezing + Storage of frozen sperm in the cryobank for 6 months — 200.00 EUR (400.00 BGN).
• Testicular Tissue Freezing + Storage of testicular tissue in the cryobank for 6 months — 300.00 EUR (600.00 BGN).

Embryo Vitrification: 

• Embryo Vitrification (up to 4 embryos will be vitrified in cryogenic vial(s)/cryotube(s)/cryogenic tube(s)) + 6 months of storage in the cryobank — 250.00 EUR (500.00 BGN).
• Embryo Vitrification (5–8 embryos will be vitrified in cryogenic vial(s)/cryotube(s)/cryogenic tube(s)) + 6 months of storage in the cryobank — 300.00 EUR (600.00 BGN).
• Embryo Vitrification (9 and more embryos (large embryonic cohort) will be vitrified in cryogenic vial(s)/cryotube(s)/cryogenic tube(s)) + 6 months of storage in the cryobank — 350.00 EUR (700.00 BGN).

Storage of frozen oocytes/sperm/embryos: 

• Storage of vitrified oocytes/sperm/embryo(s) in the cryobank for 1 month — 15.00 EUR (30.00 BGN).
• Storage of vitrified oocytes/sperm/embryo(s) in the cryobank for 6 months — 75.00 EUR (150.00 BGN).
• Storage of vitrified oocytes/sperm/embryo(s) in the cryobank for 12 months — 140.00 EUR (280.00 BGN).
• Oncofertility preservation: storage of the of vitrified oocytes/sperm/embryo(s) in the cryobank — 50% Discount.

IUI Treatment:

• Sperm prep. for IUI — 90.00 EUR (180.00 BGN). 
• IUI with the partner’s sperm (1 cycle) — 180.00 EUR (360.00 BGN).
• IUI with the partner’s sperm (follow–up insemination performed in the same IUI cycle) — 75.00 EUR (150.00 BGN).

DUI (IUI with the Donor’s Sperm): 

• Sperm prep. for IUI — 90.00 EUR (180.00 BGN). 
• IUI with the Donor’s Sperm (1 cycle) — 260.00 EUR (520.00 BGN).
• IUI with the Donor’s Sperm (follow–up insemination performed in the same IUI cycle) — 125.00 EUR (250.00 BGN).

Prenatal Consultations & Screenings: 

• Prenatal consultation with Ob.–Gyn. + ultrasound scan (10 weeks pregnant and more) — 35.00 EUR (70.00 BGN). 
• Pelvic ultrasound scan (up to week 12 of pregnancy) — 27.50 EUR (55.00 BGN). 
• Fetal Morphology Ultrasound Scan (singleton pregnancy; 20–22 weeks fetus) — 50.00 EUR (100.00 BGN).
• Fetal Morphology Ultrasound Scan (twin pregnancy; 20–22 weeks fetuses) — 60.00 EUR (120.00 BGN).
• Third–trimester Doppler ultrasound scan/26–40 Week Pregnancy Scan/ Fetal ultrasound scan of the third trimester (singleton pregnancy) — 40.00 EUR (80.00 BGN). 
• Third–trimester Doppler ultrasound scan/26–40 Week Pregnancy Scan/ Fetal ultrasound scan of the third trimester (twin pregnancy) — 50.00 EUR (100.00 BGN).
• Fetal Heart Monitoring/ Testing Fetal Heart Rate (monitoring your baby’s heartbeat using Doppler ultrasound scan; 20 min.) — 12.50 EUR (25.00 BGN). 
• Medication Response Genetic Test/ Clinical test for Drug metabolism or response (Pharmacogenomic Tests) — 25.00 EUR (50.00 BGN). 
• First Trimester Prenatal Screening Tests (early screening): First Trimester biochemical testing at 11–14 weeks (first–trimester maternal serum screening using biochemical markers /Biochemical tests for abnormalities in pregnancy) + ultrasound scanning at 11–14 weeks (singleton pregnancy and twin pregnancy) — 60.00 EUR (120.00 BGN).
• Second Trimester Prenatal Screening Tests (late screening): Second Trimester biochemical testing at 15–19 weeks (first–trimester maternal serum screening using biochemical markers /Biochemical tests for abnormalities in pregnancy) + ultrasound scanning at 15–19 weeks — 60.00 EUR (120.00 BGN) for singleton pregnancy; and 70.00 EUR (140.00 BGN) for twin pregnancy. 

Labor & Delivery: 

• Natural birth — 550.00 EUR (1,100.00 BGN). 
• C–Section Birth (Cesarean section: singleton pregnancy) — 700.00 EUR (1,400.00 BGN). 
• C–Section Birth (Caesarean Section of Multifetal Pregnancy) — 800.00 EUR (1,600.00 BGN). 

Conclusion

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