SUMMARY: In FIV Marbella we offer standard embryo adoption bundles (IVF with embryo adoption). Embryo adoption cycles are authentic ones. Embryo adoption is an ideal alternative to thousands of standard IVF cycles for the couples with severe fertility issues when it is impossible to pick–up the mature oocyte or retrieve the sperm with normal morphology and normal genetic content’s “portfolio.” If there are severe issues with chromosomal configuration, with DNA configuration, with morphological configuration and the chances to have the tiny bundle of joy using own gametes is under 10% in every standard IVF cycle, embryo adoption is the top priority option that can be proposed by FIV Marbella fertility experts.
Embryo adoption cycles are more powerful. With extreme performance. And more PRO. Stunning opportunities to have a small bundle of joy with ideal selection technology. As every IVF cycle, the embryo adoption cycle has one Top Option: multi–synchronization of additional techniques and options that are “tuned up” exclusively for every case). Embryo adoption cycle is less expensive if compared with the standard IVF cycle as there is no controlled ovarian stimulation protocol (no injectable hormones, oral pills, and Trigger shot) and no egg retrieval surgery (no anesthesia and the oocyte pick–up). Instead, there is an endometrium preparation for embryo transfer but the medications that are used for it is less expensive than for controlled ovarian stimulation.
PRICE: Embryo adoption package: Price on Request.
More details about embryo adoption cycle in FIV Marbella.
Embryo adoption cycles are proposed for the couples with severe fertility issues where both require donated gametes (donated oocytes and donated sperm). It is possible to adopt the embryos from the other couples with similar characteristics or to generate the embryos with the “desired” configuration using the donated oocytes from the egg donor and the donated sperm from the sperm donor through convenient fertilization (or through /ICSI/IMSI fertilization techniques) and embryo culturing.
Both options (to adopt the already generated embryo (fresh or vitrified) or to generate the embryo with desired “configuration” using egg donation and sperm donation options.
IVF cycles with embryo generation ‘event’ involving oocyte donation and the sperm donation are dual–staged ones. The oocyte donor is selected according to the set criteria: with the same physical characteristics, with the similar appearance (as it is vital for the couple to have the tiny one looking like his or her mother (having the resemblance with the mother), with the blood group (as the patient), with the similar genetic content (to exclude the genetic abnormalities, chromosomal abnormalities, and abnormalities that affect the genomes). La cual ha pasado por exhaustivas pruebas y análisis para descartar la presencia de enfermedades como el VIH o la Hepatitis, entre otros.
The sperm donor is also selected according to the set criteria: with the same physical characteristics, with the similar appearance (as it is vital for the couple to have the tiny one looking like his or her father (having the resemblance with the father), with the blood group (as the patient), with the similar genetic content (to exclude the genetic abnormalities, chromosomal abnormalities, and abnormalities that affect the genomes).
If the embryo is adopted from the other couple.
STEP 1 | INITIAL CONSULTATION with FIV Marbella Fertility Expert (or with FIV Marbella Fertility Experts, in case if necessary). Selection of the embryo for further embryo adoption.
Your FIV Marbella fertility expert will propose you to adopt the embryo from the couple that donated their embryo for being adopted by the others. In FIV Marbella, we have the database with the embryonic portfolios for embryo adoption. Every embryo has its own profile with the complete information about his/her mother and father (their physical characteristics, the blood group, and the genetic content “configuration.”
You both will choose the embryo with desired “configuration” and will discuss it with your FIV Marbella fertility expert.
STEP 2 | The patient’s pre–treatment screening and controlled endometrium preparation.
You both will undergo pre–treatment screening tests, after that your fertility expert will discuss with you both the obtained results and will select with you the embryo that ideally suits you. You will start the endometrium preparation cycle. The endometrium preparation protocol is drafted, discussed and implemented prior the embryo transfer “event.” The patient is prescribed the oral estrogen or transdermal patches to prepare her uterus for the actual embryo transfer.
STEP 3 | “Validation” of the endometrium preparation for the actual embryo transfer.
The patient’s endometrium preparation is monitored via ultrasound scans and blood tests. This dual–control authentication system turns it possible to visualize what is “going on inside,” and to show the time frame for the actual embryo transfer according to the stage of the endometrium receptivity, thus boosting the embryo implantation chances.
STEP 4 | Embryo selection for the actual embryo transfer.
The time frame for the actual embryo transfer is chosen and scheduled. Prior to embryo transfer, the embryos are investigated, and the top–quality embryos (usually one or two) are chosen for the embryo transfer.
STEP 5 | Embryo transfer and pregnancy test pre–scheduling.
Ultimately, the embryo transfer is performed, and the pregnancy test is scheduled in two weeks after the embryo transfer. If the pregnancy test is positive, the fertility expert will schedule the early ultrasound scan that would visualize the embryonic heart activity as early as week 6 or week 8.
If the couple’s decision is to generate the embryos from the donated oocytes (using the already vitrified oocytes from the egg donor) and from donated sperm (using the already vitrified sperm from the sperm donor).
STEP 1 | INITIAL CONSULTATION with FIV Marbella Fertility Expert (or with FIV Marbella Fertility Experts, in case if necessary). Selection of the oocyte donor and the sperm donor for further embryo generation event.
Step 1 will be similar except one thing: the couple will choose the oocyte’s donor and the sperm donor whose gametes will be used for the embryo generation “event.”
STEP 2 | The patient’s pre–treatment screening and controlled endometrium preparation.
Step 2 is the same as for the embryo adoption.
STEP 3 | “Validation” of the endometrium preparation for the actual embryo transfer.
Step 3 is the same as for the embryo adoption.
STEP 3 | Thawing of the oocytes and sperm. Fertilizing the oocytes with sperm.
Earlier vitrified oocytes and sperm will be thawed (warmed) three or six days earlier than your embryo transfer (ET) is scheduled. After thawing, every oocyte will be fertilized with sperm (conventional fertilization) or using ICSI/IMSI fertilization technique.
STEP 4 | EMBRYO CULTURING
Once the oocytes are fertilized with sperm, it is now called “an embryo” which is left to grow in special culture media, usually for three days following a rigorous process of observation of their morphology and cell number. The embryonic cohort for embryo transfer, even being large has its own criteria. Some embryos are mosaic and should be excluded from the embryonic cohort that is ideal for further embryo transfer event. Some embryos may stop their development and cannot be transferred because they are not viable.
In some cases, the embryo is left to grow up to six days (blastocyst stage) in order to select more rigorously their morphology and decide which are most likely to implant in the uterus of the patient after Embryo Transfer and which are susceptible for freezing (Embryo Vitrification). The embryologists will track the embryos’ quality as it is the leading indicator for the embryos that are the most powerful to implant in the womb after being transferred there.
STEP 5 | “Validation” of the endometrium preparation for the actual embryo transfer.
The patient’s endometrium preparation is monitored via ultrasound scans and blood tests. This dual–control authentication system turns it possible to visualize what is “going on inside,” and to show the time frame for the actual embryo transfer according to the stage of the endometrium receptivity, thus boosting the embryo implantation chances.
STEP 6 | Embryo selection for the actual embryo transfer.
The time frame for the actual embryo transfer is chosen and scheduled. Prior to embryo transfer, the embryos are investigated, and the top–quality embryos (usually one or two) are chosen for the embryo transfer.
STEP 7 | EMBRYO TRANSFER
Embryo transfer is a simple, non–invasive, painless, short–time procedure that does not need anesthesia or sedative medications. It is scheduled and performed on day 3 or day 6 (embryo culturing). One or two embryos are transferred into the maternal uterus through a special flexible tube (catheter). Embryo transfer is performed on an outpatient basis and after embryo transfer is completed, the patient is recommended to rest for 24—48 hours.
STEP 8 | EMBRYO VITRIFICATION
On the day of embryo transfer “event”, remaining viable embryos are frozen using a vitrification technique, for future transfer in a subsequent cycle without starting an ovarian stimulation protocol and oocyte retrieval. Embryo freezing (embryo cohort freezing) for further frozen embryo transfer cycles is an essential component of a successful IVF, with vitrification technique providing top embryo survival ratings and excellent pregnancy outcomes. Every couple and every patient can choose embryo vitrification and embryo storage for future FET cycles.
STEP 9 | PREGNANCY TEST
Two weeks after the embryo transfer “event”, the patient will return to FIV Marbella for a pregnancy test. The blood test will be performed to measure hCG hormone levels and if they are increased, the pregnancy is achieved. hCG hormone is a specific hormone that is produced by the placenta after the embryo implantation event.
The urinary test will be performed two weeks later. If the patient is pregnant, the early ultrasound scan will be pre–scheduled in two or three more weeks (early ultrasound detects embryonic heart activity starting from week 6 or week 7 in pregnancy).
STEP 10 | EARLY ULTRASOUND SCAN
Early ultrasound scan is performed to detect the heart activity of the embryo and to confirm the pregnancy. If the ultrasound technician can see the sparkling dot on the screen that is the embryonic heart. If the embryonic heart has a normal heartbeat rate, that seems that embryo is viable, and the embryonic heart is developing.
If the couple’s decision is to generate the embryos from the donated oocytes (using the already vitrified oocytes from the egg donor) and from donated sperm (using the already vitrified sperm from the sperm donor).
STEP 1 | INITIAL CONSULTATION with FIV Marbella Fertility Expert (or with FIV Marbella Fertility Experts, in case if necessary). Selection of the egg donor.
IVF cycles with oocyte donation are the dual–staged ones. The oocyte donor is selected according to the set criteria: with the same physical characteristics, with the similar appearance (as it is vital for the couple to have the tiny one looking like his or her mother (having the resemblance with the mother), with the blood group (as the patient), with the similar genetic content (to exclude the genetic abnormalities, chromosomal abnormalities, and abnormalities that affect the genomes). La cual ha pasado por exhaustivas pruebas y análisis para descartar la presencia de enfermedades como el VIH o la Hepatitis, entre otros.
The sperm donor is also selected according to the set criteria: with the same physical characteristics, with the similar appearance (as it is vital for the couple to have the tiny one looking like his or her father (having the resemblance with the father), with the blood group (as the patient), with the similar genetic content (to exclude the genetic abnormalities, chromosomal abnormalities, and abnormalities that affect the genomes).
STEP 2 is started for you and for the oocyte donor synchronically, therefore, it is ‘labeled’ step 2 for you both.
STEP 2 | Egg donor pre–treatment screening and controlled ovarian stimulation.
The oocyte donor is screened before the IVF cycle. After the pre–treatment screening results are obtained, the oocyte donor undergoes ovarian stimulation and oocyte retrieval (oocyte pick–up) procedure.
STEP 2 | The patient’s pre–treatment screening and controlled endometrium preparation.
The patient undergoes pre–treatment screening tests and the endometrium preparation cycle. The endometrium preparation protocol is drafted, discussed and implemented prior the oocyte’s fertilization “event.” The patient is prescribed the oral estrogen or transdermal patches to prepare her uterus for the actual embryo transfer synchronously with the oocyte donor’s ovarian stimulation cycle.
STEP 3 | Sperm collection and sperm preparation.
The donor’s sperm is collected and prepared for further fertilization the same day as the oocyte donor has her oocyte retrieval (oocyte pick–up) procedure.
STEP 4 | Fertilization and embryo culturing.
Collected oocytes are comprehensively investigated, fertilized with the partner’s sperm or with the donor’s sperm. After fertilization, the newly generated embryos are cultured into the incubator (2–5 days), and their development is continuously monitored by the embryologist.
STEP 5 | “Validation” of the endometrium preparation for the actual embryo transfer.
The patient’s endometrium preparation is monitored via ultrasound scans and blood tests. This dual–control authentication system turns it possible to visualize what is “going on inside,” and to show the time frame for the actual embryo transfer according to the stage of the endometrium receptivity, thus boosting the embryo implantation chances.
STEP 6 | Embryo selection for the actual embryo transfer and vitrification of the embryonic cohort that is left for the future frozen embryo transfer cycles.
The time frame for the actual embryo transfer is chosen and scheduled. Prior to embryo transfer, the embryos are investigated, and the top–quality embryos (usually one or two) are chosen for the embryo transfer. The remaining viable embryonic cohort is vitrified on the same day for future frozen embryo transfer cycles.
STEP 7 | Embryo transfer and pregnancy test pre–scheduling.
Ultimately, the embryo transfer is performed, and the pregnancy test is scheduled in two weeks after the embryo transfer. If the pregnancy test is positive, the fertility expert will schedule the early ultrasound scan that would visualize the embryonic heart activity as early as week 6 or week 8.